Protective and therapeutic role for [alpha]-B-crystallin in autoimmune demyelination

Article Abstract:

The pathophysiological implications of the immune response of [alpha]B-crystallin (CRYAB) in autoimmune demyelination are investigated. It is shown that the immune response against a negative regulator of inflammation, CRYAB, in multiple sclerosis, would intensity inflammation and demyelination, which is countered by giving CRYAB itself for therapy of ongoing disease.

United States, Health aspects, Analysis, Genetic aspects, Myelin proteins, Cytokines, Demyelinating diseases, Western immunoblotting, Western blot

---

Collateral damage repaired

Article Abstract:

Researchers are investigating ways to repair neurological collateral damage caused by multiple sclerosis in mice by delivering neural precursor cells to the blood or spinal fluid. The article concludes that the success of these experiments has implications for the reversal of damage in humans with spinal cord damage and multiple sclerosis.

Care and treatment, Multiple sclerosis, Neurology, Immunological research, Immunologic research

---

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets

Article Abstract:

The technique of proteomic analysis is employed to explain the neuropathology of three major types of multiple sclerosis (MS) lesions. The MS lesions are found to be extremely beneficial in the development of new therapeutic strategies and targets.

HEALTH SERVICES, Ambulatory Health Care Services, Therapeutic Procedures, Therapeutics, Homeopathy, Proteomics, Sclerosis

Similar abstracts:

• Abstracts: Putting theory into practice: Wildlife health in conservation. Conservation medicine: A veterinary perspective
• Abstracts: Evidence from U-Th dating against Northern Hemisphere forcing of the penultimate deglaciation. Extending the Vostok ice-core record of palaeoclimate to the penultimate glacial period
• Abstracts: Protecting Africa's elephants: a historical commitment. The balance of nature. The elephant wars
• Abstracts: Petition calls for clampdown on absentee Chinese researchers. Young guns shoot to the top in China's research revolution
• Abstracts: Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Crystal structure of a transcription factor IIIB core interface ternary complex

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.